Skip to Content
MilliporeSigma
All Photos(1)

Documents

A7926

Sigma-Aldrich

Azlocillin sodium salt

Synonym(s):

D-α-([Imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
C20H22N5O6SNa
CAS Number:
Molecular Weight:
483.47
EC Number:
MDL number:
UNSPSC Code:
51282412
PubChem Substance ID:
NACRES:
NA.85

form

powder

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

room temp

SMILES string

[Na+].CC1(C)SC2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)c4ccccc4)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C20H23N5O6S.Na/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30;/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29);/q;+1/p-1/t11-,12-,13+,16-;/m1./s1

InChI key

UVOCNBWUHNCKJM-XFAPPKAWSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Chemical structure: ß-lactam

Application

Azlocillin is often used against <l>Pseudomonas aeruginosa </l>and has been used to develop novel antibiotic quantitation techniques .

Biochem/physiol Actions

Azlocillin is a semisynthetic penicillin and a β-lactam antibiotic. It acts by inhibition of penicillin-binding protein (PBP)-dependent bacterial cell wall synthesis.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A Weber et al.
Antimicrobial agents and chemotherapy, 24(5), 750-753 (1983-11-01)
We describe a rapid, precise, and simple procedure for the quantitation of azlocillin in serum and in aqueous solutions by high-pressure, reverse-phase liquid chromatography. This method uses a single precipitation step, detection by dual-wavelength monitoring (220 and 254 nm), and
Structure-Activity Relationships of Different β-Lactam Antibiotics against a Soluble Form of Enterococcus faecium PBP5, a Type II Bacterial Transpeptidase.
Andrea M. Hujer, Malgosia Kania, et. Al
Journal of Affective Disorders, 49, 612-618 (2005)
Venkata Raveendra Pothineni et al.
Scientific reports, 10(1), 3798-3798 (2020-03-04)
Lyme disease is one of most common vector-borne diseases, reporting more than 300,000 cases annually in the United States. Treating Lyme disease during its initial stages with traditional tetracycline antibiotics is effective. However, 10-20% of patients treated with antibiotic therapy

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service