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Key Documents

A7252

Supelco

Ajmaline

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About This Item

Empirical Formula (Hill Notation):
C20H26N2O2
CAS Number:
Molecular Weight:
326.43
EC Number:
MDL number:
UNSPSC Code:
41116107

storage temp.

2-8°C

SMILES string

CCC1C(O)N2C3CC1C4C(O)C5(CC24)[C@H]3N(C)c6ccccc56

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Biochem/physiol Actions

Indole alkaloid from Rauwolfia serpentina that is a Class Ia antiarrhythmia compound. It blocks sodium channels in skeletal and cardiac muscle and cardiac HERG potassium channels in the open state but not in the closed state. Ajmaline administered intravenously prolongs the atrioventricular (AV) conduction times in the heart and has been used diagnostically to detect AV block and other cardiac abnormalities.

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Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Certificates of Analysis (COA)

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