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B2629

Betaine

From sugar beets, ≥98% (perchloric acid titration), choline metabolite, powder or crystals

Synonym(s):

(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

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About This Item

Linear Formula:
(CH3)3N+CH2COO-
CAS Number:
107-43-7
Molecular Weight:
117.15
NACRES:
NA.77
PubChem Substance ID:
24891663
UNSPSC Code:
12352202
EC Number:
203-490-6
MDL number:
MFCD00012123
Beilstein/REAXYS Number:
3537113

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Product Name

Betaine, ≥98% (perchloric acid titration)

biological source

sugar beets

Quality Level

200

assay

≥98% (perchloric acid titration)

form

powder or crystals

mp

310 °C (dec.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3

InChI key

KWIUHFFTVRNATP-UHFFFAOYSA-N

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Betaine ≥98% (perchloric acid titration)

Sigma-Aldrich

B2629

Betaine

Betaine solution 5 M, PCR Reagent

Sigma-Aldrich

B0300

Betaine solution

Betaine BioUltra, ≥99.0% (NT)

Sigma-Aldrich

61962

Betaine

Betaine ≥98%

Sigma-Aldrich

W422312

Betaine

assay

≥98% (perchloric acid titration)

assay

-

assay

≥99.0% (NT)

assay

≥98%

biological source

sugar beets

biological source

-

biological source

-

biological source

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

-

form

powder or crystals

form

liquid

form

-

form

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

methanol: 1 M at 20 °C, clear, colorless

solubility

-

General description

Betaine is a quaternary ammonium zwitterion, extensively present in animals, plants and microorganisms. It also forms a good dietary source as it is found in wheat, spinach, shellfish and sugar beets. Betaine is a methyl derivative of the amino acid glycine. It is known by different names such as trimethylglycine, glycine betaine, lycine and oxyneurine.[1]

Application

Betaine has been used to study the effects of antioxidants on regrowth from cryopreservation.

Biochem/physiol Actions

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.
Apart from betaine taking part in transmethylation, it acts as an organic osmolyte in protecting cells under stress. This is being significantly observed in plants and microorganisms.[1] Betaine is also known to increase the levels of S-adenosylmethionine and thus this might reduce the effects of hepatic steatosis.[2]

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR8542
MKCZ0677
MKCZ1275
MKCZ0680
MKCS1839

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Antioxidant and anti-stress compounds improve regrowth of cryopreserved Rubus shoot tips
Uchendu EE, et al.
In Vitro Cellular & Developmental Biology, 46(4), 386-393 (2010)
Jindong Hao et al.
Animals : an open access journal from MDPI, 11(6) (2021-07-03)
m6A is one of the most common and abundant modifications of RNA molecules present in eukaryotes. The methyltransferase complex, consisting of methyltransferase-like 3 (METTL3), METTL14, and WTAP, is responsible for the m6A modification of RNA. WTAP was identified as an
L Garcia-Gonzalez et al.
International journal of food microbiology, 129(3), 253-263 (2009-01-23)
High pressure carbon dioxide (HPCD) treatment is currently considered as an attractive non-thermal process for preserving food. Industrial application of this technique requires, among others, systematic (quantitative) data on the inactivation of food relevant pathogenic and spoilage microorganisms, and in-depth
Lei Gao et al.
International journal of molecular sciences, 22(14) (2021-07-25)
The effective cryopreservation of mesenchymal stem cells (MSCs) is indispensable to the operation of basic research and clinical transplantation. The prevalent protocols for MSC cryopreservation utilize dimethyl sulfoxide (DMSO), which is easily permeable and able to protect MSCs from cryo-injuries
Yuna Choi et al.
Experimental neurobiology, 30(4), 308-317 (2021-09-07)
Experimental autoimmune uveitis (EAU) is an animal model of human autoimmune uveitis that is characterized by the infiltration of autoimmune T cells with concurrent increases in pro-inflammatory cytokines and reactive oxygen species. This study aimed to assess whether betaine regulates
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Product Information Sheet - B2629

Product Information Sheet

Global Trade Item Number

SKUGTIN
B2629-100G04061835540679
B2629-1KG04061833426968
B2629-50G04061835540686

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