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Key Documents

22048

Sigma-Aldrich

κ-Carrageenan

sulfated plant polysaccharide

Synonym(s):

Vegetable gelatin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

plant

form

powder

color

white to off-white

viscosity

5-25 mPa.s, 0.3 % in H2O(25 °C)

solubility

H2O: soluble 5 mg/mL (hot)

InChI

1S/C24H38O25S2/c25-1-5-14(48-50(33,34)35)9(27)10(28)22(42-5)45-16-8-4-40-19(16)12(30)23(44-8)47-20-13(31)24(43-6(2-26)17(20)49-51(36,37)38)46-15-7-3-39-18(15)11(29)21(32)41-7/h5-32H,1-4H2,(H,33,34,35)(H,36,37,38)/p-2/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14+,15+,16+,17+,18-,19-,20-,21+,22+,23-,24+/m1/s1

InChI key

ZNOZWUKQPJXOIG-XSBHQQIPSA-L

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General description

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.
insoluble in hot concentrated salt solutions

Application

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
May be used in immobilization of microbial cells based on the growth of cell in gel

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Immobilization of cells in carrageenan.
I Chibata et al.
Methods in enzymology, 135, 189-198 (1987-01-01)
M. Wada et al.
Europ. J. Appl. Microbiol. Biotechnol., 8, 241-241 (1979)
Bakti B Sedayu et al.
Polymers, 12(5) (2020-05-21)
Carrageenans obtained from seaweeds can be processed into films for a range of applications including food packaging. The level of carrageenan refinement during extraction can influence the key properties, with semi-refined carrageenan (SRC) containing more impurities than the more refined
Manuel López-López et al.
Pharmaceutics, 11(2) (2019-02-02)
In this work, poly(lactic-co-glycolic acid) (PLGA) and chitosan (CS) nanoparticles were synthesized with the purpose of encapsulating levofloxacin (LEV). A thorough study has been carried out in order to optimize the preparation of LEV-loaded polymeric nanoparticles (NPs) suitable for parenteral
E. Castillo et al.
Applied Biochemistry and Biotechnology, 34-35, 477-477 (1992)

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