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06372

Sigma-Aldrich

β-Hydroxypyruvic acid

≥95.0% (dry substance, T)

Synonym(s):

3-Hydroxy-2-oxopropanoic acid

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About This Item

Empirical Formula (Hill Notation):
C3H4O4
CAS Number:
1113-60-6
Molecular Weight:
104.06
MDL number:
MFCD00083380
UNSPSC Code:
12352204
PubChem Substance ID:
329748234
NACRES:
NA.32

assay

≥95.0% (dry substance, T)

form

powder and chunks

impurities

≤15.0% water

storage temp.

2-8°C

SMILES string

OC(C(CO)=O)=O

InChI

1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7)

InChI key

HHDDCCUIIUWNGJ-UHFFFAOYSA-N

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Application


  • Hydroxy(phenyl)pyruvic acid reductase in Actaea racemosa L.: a putative enzyme in cimicifugic and fukinolic acid biosynthesis.: This study investigates the role of ß-Hydroxypyruvic acid in the biosynthesis of bioactive compounds in Actaea racemosa, highlighting its importance in plant secondary metabolism and potential applications in medicinal chemistry (Jahn and Petersen, 2024).

  • The gut microbiota confers protection in the CNS against neurodegeneration induced by manganism.: Research shows the protective role of ß-Hydroxypyruvic acid derivatives produced by gut microbiota against neurodegenerative conditions, providing insights into therapeutic strategies for neurological disorders (Wang et al., 2020).

Biochem/physiol Actions

Metabolite involved in the pathway of carbon in photorespiration.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

hcodes

H302,H314

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Perera et al.
Free radical research, 26(2), 145-157 (1997-02-01)
The chemical reactivity of various alpha-keto acid anions (beta-hydroxypyruvate, beta-phenylpyruvate, 2-ketobutyrate and 2-ketoglutarate) with hydrogen peroxide (H2O2) was investigated at physiological pH (7.4) and a temperature of 25 degrees C. The initial concentration of the alpha-keto acid anions was kept
Chao Gao et al.
Bioresource technology, 131, 552-554 (2013-02-19)
In this work, bio-oxidation of glycerate was introduced for the green production of hydroxypyruvate. Whole cells of Pseudomonas sp. XP-LM were confirmed to have a good ability to produce hydroxypyruvate from glycerate. Under the optimal conditions, Hydroxypyruvate of 98.6 mM
Yaovalak Teerajetgul et al.
Urological research, 35(4), 173-178 (2007-06-15)
We studied the effects of an intravenous hydroxypyruvate load on endogenous oxalogenesis in rats receiving a standard diet or a vitamin-B6-deficient diet. Twelve male Wistar rats were randomized to two groups and were fed either a standard diet or a
S Matosevic et al.
Journal of biotechnology, 155(3), 320-329 (2011-08-03)
Complex molecules are synthesised via a number of multi-step reactions in living cells. In this work, we describe the development of a continuous flow immobilized enzyme microreactor platform for use in evaluation of multi-step bioconversion pathways demonstrating a de novo
M Legge
Biochimica et biophysica acta, 1355(2), 99-101 (1997-02-04)
Mouse oocytes and zygotes, when solubilised demonstrated that a range of ketoaldehydes could be utilised as substrates. Of the five ketoaldehydes investigated the overall substrate utilisation was hydroxypyruvate > glyoxylate > 2-ketobutyrate > pyruvate > glycolate. The utilisation of these
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