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Y0000480

Dibrompropamidine diisetionate

European Pharmacopoeia (EP) Reference Standard

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10 MG
$156.00

$156.00


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10 MG
$156.00

About This Item

Empirical Formula (Hill Notation):
C21H30Br2N4O10S2
CAS Number:
Molecular Weight:
722.42
UNSPSC Code:
41116107
NACRES:
NA.24

$156.00


Available to ship onMarch 31, 2025Details


Request a Bulk Order

grade

pharmaceutical primary standard

API family

dibrompropamidine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[S](=O)(=O)(O)CCO.Brc1c(ccc(c1)\C(=N\[H])\N)OCCCOc2c(cc(cc2)\C(=N\[H])\N)Br

InChI

1S/C17H18Br2N4O2.C2H6O4S/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19;3-1-2-7(4,5)6/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23);3H,1-2H2,(H,4,5,6)

InChI key

BZACJASHKPPTKX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

application

Dibrompropamidine diisetionate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

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M R Richards et al.
The Journal of pharmacy and pharmacology, 46(7), 563-566 (1994-07-01)
Combinations of polymyxin B and dibromopropamidine isethionate exhibited synergistic inhibitory and bactericidal activity against Pseudomonas aeruginosa, Enterobacter cloacae, Proteus mirabilis, Escherichia coli and Staphylococcus aureus. Similar results were obtained with polymyxin B plus propamidine combinations except that propamidine was not
A M Beattie et al.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 25(5), 260-262 (1990-08-01)
We describe a case of Acanthamoeba keratitis related to soft contact lens wear. The patient presented with a 3-week history of severe uniocular pain, radial stromal infiltrates and subepithelial infiltrates with no epithelial defect. Acanthamoeba was cultured from the corneal
R M Richards et al.
Journal of pharmaceutical sciences, 82(9), 975-977 (1993-09-01)
Electron micrographs of log-phase Pseudomonas aeruginosa and Enterobacter cloacae cultured for 4 h in the presence of subinhibitory concentrations of dibromopropamidine isethionate indicate that this antibacterial agent can cause marked damage to the cell envelope structures of both species. This
S S Asghar et al.
Biochimica et biophysica acta, 317(2), 539-548 (1973-08-30)
A series of amidino compounds has been investigated for their inhibitory effects on C1s, C1r, and generation of C1s. Diamidines consisting of two amidinophenyl residues linked in para position by a molecular bridge proved to be the strongest competitive inhibitors
P Plesiat et al.
Journal of bacteriology, 179(22), 7004-7010 (1997-11-26)
Testosterone (a strongly hydrophobic steroid) and testosterone hemisuccinate (a negatively charged derivative) were used as probes to investigate alterations in the outer membrane of Pseudomonas aeruginosa. Diffusion rates of the steroids across the lipid bilayer were measured by coupling the

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