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Millipore

Astragaloside IV

>98.0%

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1 MG
$384.00

$384.00


Estimated to ship onMay 03, 2025


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1 MG
$384.00

About This Item

Empirical Formula (Hill Notation):
C41H68O14
CAS Number:
Molecular Weight:
784.97
MDL number:
UNSPSC Code:
41106200
PubChem Substance ID:
NACRES:
NA.85

$384.00


Estimated to ship onMay 03, 2025


Request a Bulk Order

Quality Level

assay

≥98.0% (TLC)
>98.0%

form

powder

mp

295-296 °C (lit.)

SMILES string

CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O

InChI

1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

InChI key

QMNWISYXSJWHRY-YLNUDOOFSA-N

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Biochem/physiol Actions

Anti-inflammatory.

Other Notes

Chemical constituent of Astragali radix[1][2]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Wenya Shan et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(1), 85-88 (2012-06-30)
To provide a scientific basis for the drug-combination and aim to examine whether astragaloside IV has the impact on the cytochrome P450 enzymes. Tolbutamide, chlorzoxazone, coumarin, nifedipine, and phenacetin were as probe substrates of rat CYP2C9, CYP2E1, CYP2A6, CYP3A4, and
Dingkun Gui et al.
PloS one, 7(6), e39824-e39824 (2012-06-30)
Glucose-induced reactive oxygen species (ROS) production initiates podocyte apoptosis, which represents a novel early mechanism leading to diabetic nephropathy (DN). Here, we tested the hypothesis that Astragaloside IV(AS-IV) exerts antioxidant and antiapoptotic effects on podocytes under diabetic conditions. Apoptosis, albuminuria
I. Kitagawa et al.
Chemical & Pharmaceutical Bulletin, 31, 698-698 (1983)
Ming Hao et al.
Zhonghua yi xue za zhi, 92(30), 2104-2107 (2012-11-20)
To explore the protective effects of astragaloside IV on retinal ganglion cells (RGC) incubated under high glucose. Cultured RGC-5 were divided into 3 groups: control, high glucose and high glucose+astragaloside IV. The survival rate of cell was measured by CCK-8
Li-Hua Peng et al.
Biological & pharmaceutical bulletin, 35(6), 881-888 (2012-06-13)
Topical delivery of therapeutic agents at the time of injury to accelerate skin repair and prevent the formation of scars during the wound healing process has received increasing attention and represents a novel regenerative and prophylactic strategy for wound treatment.

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