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46149

Supelco

Corticosterone 21-acetate

VETRANAL®, analytical standard

Synonym(s):

11β,21-Dihydroxy-4-pregnene-3,20-dione 21-acetate, 4-Pregnene-11β,21-diol-3,20-dione 21-acetate

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About This Item

Empirical Formula (Hill Notation):
C23H32O5
CAS Number:
Molecular Weight:
388.50
Beilstein/REAXYS Number:
3225312
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)[C@H](CC[C@@]24[H])C(=O)COC(C)=O

InChI

1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1

InChI key

WKQCPUMQBMFPLC-ZWFCQKKLSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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H Okahata et al.
Acta endocrinologica, 112(3), 383-387 (1986-07-01)
The effects of dietary changes from breast milk to solid food and corticosterone acetate administration on somatostatin-like immunoreactivity (SLI) in the gastric antrum and corpus were studied in young and adult rats. At 7 days of age, a single dose
M Qulali et al.
Alcoholism, clinical and experimental research, 16(3), 427-431 (1992-06-01)
Glucocorticoids induced ADH activity and mRNA 2- to 4-fold in rat hepatoma cells (H4IIE and H4IIEC3), but were reported not to alter ADH activity in rat liver. The failure of corticosteroids to induce ADH may have been due to the
D Filipini et al.
The Journal of steroid biochemistry and molecular biology, 39(2), 245-252 (1991-08-01)
The effects of various steroid hormones on the long-term potentiation (LTP) of the rat hippocampus were evaluated. LTP was elicited in the dentate gyrus of adrenalectomized animals with priming tetanic stimulation (200 Hz-0.03 cps) of its main afferent, the perforant
J T Vreeburg et al.
Journal of steroid biochemistry, 29(1), 93-98 (1988-01-01)
Corticosterone acetate (10 mg/day) was administered to gonadectomized and adrenalectomized male rats bearing 5, 10 or 15 mm long testosterone filled silicone elastomer capsules. It was found that the serum testosterone levels induced by these capsules were not influenced by
H Okahata et al.
Acta endocrinologica, 111(4), 539-545 (1986-04-01)
The effects of weaning (abrupt dietary changes from breast milk to solid food) and corticosterone injection on antral gastrin-like immunoreactivity (G-LI) concentrations and antral G-LI biosynthesis were studied in rats. A single dose of corticosterone acetate was injected in one

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