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Prochloraz

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C15H16Cl3N3O2
CAS Number:
Molecular Weight:
376.67
Beilstein/REAXYS Number:
8155344
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n2ccnc2

InChI

1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3

InChI key

TVLSRXXIMLFWEO-UHFFFAOYSA-N

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General description

Prochloraz belongs to the imidazole class of fungicides, with protective and curative action, found to be effective against different fungi affecting cereal crops, turf, citrus and tropical fruit, field legumes and beet. Its mode of action involves the inhibition of ergosterol biosynthesis.

Application

Prochloraz may be used as an analytical reference standard for the quantification of the analyte in agricultural commodities using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Exclamation markEnvironment

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Determination of fungicide residues in fruits and vegetables by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry
Blasco C, et al.
Journal of Chromatography A, 947(2), 227-235 (2002)
The Pesticide Encyclopedia (2014)
Simplified determination of combined residues of prochloraz and its metabolites in vegetable, fruit and wheat samples by gas chromatography
Paoli D.M, et al.
Journal of Chromatography A, 765(1), 127-131 (1997)
Nigel C Noriega et al.
Biology of reproduction, 72(6), 1324-1335 (2005-01-28)
Prochloraz (PZ) is an imidazole fungicide that displays multiple endocrine activities. It inhibits steroid synthesis via P450 modulation and acts as an androgen receptor (AR) antagonist, but its effects on male sexual differentiation have not been described. The purpose of
Maj-Britt A Bjergager et al.
Aquatic toxicology (Amsterdam, Netherlands), 101(2), 412-422 (2011-01-11)
Laboratory experiments have shown that azole fungicides enhance the toxic effect of pyrethroid insecticides towards the aquatic crustacean Daphnia magna. Due to their sorptive properties the pesticides may, however, be less bioavailable in natural environments, possibly rendering them less toxic

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