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42258

Supelco

(S)-ar-Turmerone

analytical standard

Synonym(s):

(S)-2-Methyl-6-(4-methylphenyl)-2-hepten-4-one

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About This Item

Empirical Formula (Hill Notation):
C15H20O
CAS Number:
532-65-0
Molecular Weight:
216.32
MDL number:
MFCD09031381
UNSPSC Code:
85151701
PubChem Substance ID:
329756030

grade

analytical standard

assay

≥90.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H](CC(=O)\C=C(\C)C)c1ccc(C)cc1

InChI

1S/C15H20O/c1-11(2)9-15(16)10-13(4)14-7-5-12(3)6-8-14/h5-9,13H,10H2,1-4H3/t13-/m0/s1

InChI key

NAAJVHHFAXWBOK-ZDUSSCGKSA-N

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General description

(S)-ar-Turmerone is the major constituent of turmeric oil derived from turmeric, which can find pharmaceutical applications due to its antibacterial, anti-carcinogenic, insect-repellent, anti-oxidant and anti-fungal properties.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC8338
BCCB0284
BCBX4236
BCBW2941
BCBV3815

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Sun Young Park et al.
International immunopharmacology, 14(1), 13-20 (2012-06-26)
Amyloid β (Aβ) induces the production of neuroinflammatory molecules, which may contribute to the pathogenesis of numerous neurodegenerative diseases. Therefore, suppression of neuroinflammatory molecules could be developed as a therapeutic method. Aromatic (ar)-turmerone, turmeric oil isolated from Curcuma longa, has
Mai Fujiwara et al.
Journal of natural products, 74(1), 86-89 (2010-12-30)
Biotransformation studies conducted on (+)-(S)-ar-turmerone (1) and (+)-(S)-dihydro-ar-turmerone (2) by the fungus Aspergillus niger have revealed that 1 was metabolized to give four oxidized metabolites, (+)-(7S)-hydroxydehydro-ar-todomatuic acid (3), (+)-(7S,10E)-12-hydroxydehydro-ar-todomatuic acid (4), (+)-(7S,10E)-7,12-dihydroxydehydro-ar-todomatuic acid (5), and (+)-(7S)-15-carboxy-9,13-epoxy-7-hydroxy-9,13-dehydro-ar-curcumene (6), and (+)-(S)-dihydro-ar-turmerone (2)
Mara E M Braga et al.
Journal of agricultural and food chemistry, 51(22), 6604-6611 (2003-10-16)
Turmeric extracts were obtained from two lots of raw material (M and S) using various techniques: hydrodistillation, low pressure solvent extraction, Soxhlet, and supercritical extraction using carbon dioxide and cosolvents. The solvents and cosolvents tested were ethanol, isopropyl alcohol, and
Mingjie Ji et al.
International journal of molecular medicine, 14(2), 253-256 (2004-07-16)
This study investigated the cytotoxic effect of ar-turmerone isolated from turmeric (Curcuma longa L) on the K562, L1210, U937 and RBL-2H3 cell lines by the MTT assay. Ar-turmerone exhibited potent cytotoxicity on these cancer cell lines. The IC50 values of
Grace G L Yue et al.
Journal of medicinal food, 15(3), 242-252 (2011-12-21)
The rhizome of Curcuma longa (turmeric) is often used in Asia as a spice and as a medicine. Its most well-studied component, curcumin, has been shown to exhibit poor bioavailability in animal studies and clinical trials. We hypothesized that the
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