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Supelco

2-Naphthylamine

analytical standard

Synonym(s):

β-Naphthylamine, 2-Aminonaphthalene

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About This Item

Linear Formula:
C10H7NH2
CAS Number:
91-59-8
Molecular Weight:
143.19
Beilstein/REAXYS Number:
3939429
EC Number:
202-080-4
MDL number:
MFCD00004112
UNSPSC Code:
41116107
PubChem Substance ID:
329753849
NACRES:
NA.24

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

306 °C (lit.)

mp

111-113 °C (lit.)

density

1.061 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

Nc1ccc2ccccc2c1

InChI

1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2

InChI key

JBIJLHTVPXGSAM-UHFFFAOYSA-N

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General description

2-Naphthylamine is a carcinogenic aromatic amine which induces tumor in urinary bladder.

Application

2-Naphthylamine has been used as reference standard during isolation and identification of urinary metabolites using preparative thin-layer chromatography and gas-liquid chromatography/mass spectral analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Caution

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3097
BCCL3096
BCCG4049
BCCC2053
BCBZ3240

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Metabolic conversion of 1-and 2-nitronaphthalene to 1-and 2-naphthylamine in the rat.
Johnson, Dale E., and Herbert H. Cornish.
Toxicology and Applied Pharmacology, 46.3, 549-553 (1978)
Formation of urothelial and hepatic DNA adducts from carcinogen 2-naphthylamine.
Kadlubar FF
Carcinogenesis, 2(5), 467-470 (1981)
Weimei Sun et al.
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Inmaculada Arribas et al.
The Journal of organic chemistry, 78(8), 3997-4005 (2013-03-15)
The enantioselective catalytic hydrogenation of N-(3,4-dihydronaphthalen-2-yl) amides (1) with rhodium catalysts bearing phosphine-phosphite ligands 4 has been studied. A wide catalyst screening, facilitated by the modular structure of 4, has found a highly enantioselective catalyst for this reaction. This catalyst
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