CD5 is a transmembrane glycoprotein monomer with an Mr of 67,000. It possesses a large cytoplasmic domain suitable for signal transduction (Lozano, 1997). CD5 appears early in thymocyte development (Lozano, 1997), and is expressed at low density on thymocytes and at high density on all mature T lymphocytes (Lozano, 1997). The specificity of anti-CD5, DK23, is equivalent to that of the CD5-clustered antibody Leu-1 (Stein, 1984).
Specificity
Antibody recognizes Human CD5 antigen.
Application
Research Category Inflammation & Immunology
Research Sub Category Immunoglobulins & Immunology
This Milli-Mark Anti-CD5-FITC Antibody, clone DK23 is validated for use in FC for the detection of CD5.
Quality
Evaluated by flow cytometry using human lymphocytes
Target description
67 kDa (Lozano, 1997)
Physical form
Protein A purified
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Storage and Stability
Maintain refrigerated at 2-8°C, protected from light in undiluted aliquots for up to 6 months from date of receipt.
Analysis Note
Control human lymphocytes
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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