MAB312RX
Anti-Neuron Cell Surface Antigen Antibody, clone A2B5-105 (7), Alexa Fluor™ 488
clone A2B5-105 (7), Chemicon®, from mouse
Synonym(s):
A2B5
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100 μG
$622.00
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
conjugate
ALEXA FLUOR™ 488
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
A2B5-105 (7), monoclonal
species reactivity
mouse, chicken, human, rat
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
isotype
IgM
shipped in
wet ice
target post-translational modification
unmodified
Specificity
The antibody recognizes an epitope common to silaogangliosides and sulfatides from the plasma membranes of neurons, and neuroendocrine and glial cells. Anti-A2B5 has been used to specifically stain:
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
Immunogen
Embryonic chicken retinal cells
Application
Anti-Neuron Cell Surface Antigen Antibody, clone A2B5-105 (7), Alexa Fluor 488 detects level of Neuron Cell Surface Antigen & has been published & validated for use in IC, IH.
Immunocytochemistry
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Physical form
Purified immunoglobulin conjugated to Alexa Fluor™ 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.
Storage and Stability
Maintain at 2-8°C in undiluted aliquots in the dark for up to 6 months after date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Qinggang Xie et al.
Frontiers in nutrition, 9, 1054431-1054431 (2022-11-29)
During early neurodevelopment of infant, myelination plays an essential role in brain connectivity and emergence of behavioral and cognitive function. Early life nutrition is an important factor to shape myelination and consequently cognitive appearance. To analyze the effects of additive
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