Doublesex- and mab-3-related transcription factor 2 is encoded by the DMRT2 gene in human and directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to its early epaxial enhancer element. In addition, it is also involved in somite develoment during embryogenesis. The human protein shares a DM DNA-binding domain with Drosophila ′doublesex′ (dsx) and C. elegans mab3 gene products involved in sex determination.
Immunogen
KLH-conjugated linear peptide corresponding to human DMRT2.
Application
Anti-DMRT2 Antibody is an antibody against DMRT2 for use in Western Blotting and Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected DMRT2 in human kidney and rat testis tissue.
Research Category Epigenetics & Nuclear Function
Research Sub Category Nuclear Receptors
Quality
Evaluated by Western Blotting in human kidney tissue lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected DMRT2 in 10 µg of human kidney tissue lysate.
Target description
~70 kDa observed
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
