LYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.
Immunogen
GST-tagged recombinant protein corresponding to mouse LYAR.
Application
Anti-LYAR Antibody (Ly1 reactive clone) detects level of LYAR (Ly1 antibody reactive clone) & has been published & validated for use in WB.
Research Sub Category Immunoglobulins & Immunology
Pluripotent & Early Differentiation
Quality
Evaluated by Western Blot in mouse embryonic stem cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected LYAR in 10 µg of mouse embryonic stem cell lysate.
Target description
~48 kDa observed
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Not finding the right product?
Try our Product Selector Tool.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
