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AB3572P

Sigma-Aldrich

Anti-Organic Anion Transporting Polypeptide 2 Antibody, CT, intracellular

Chemicon®, from rabbit

Synonym(s):

oatp2, OATP-B1, Brain digoxin carrier protein

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_006446.3

UniProt accession no.

Q9Y6L6

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

rat ... Slco1A4(170698)

General description

Organic Anion Transporting Polypeptide 2 is an integral membrane protein that mediates the sodium-independent transport of organic ions, cardiac glycosides and thyroid hormones. Oatp2 is highly expressed in brain, liver, and kidney but not expressed in heart, spleen, lung, skeletal muscle, or testis.

Specificity

Recognizes rat Organic Ion Transporter 2 Polypeptide 2.

Immunogen

A 12 amino acid peptide sequence near the cytoplasmic, C-terminus of rat OATP2. The immunogen shows no significant sequence similarity to other OATPs or other proteins.

Application

Detect Organic Anion Transporting Polypeptide 2 using this Anti-Organic Anion Transporting Polypeptide 2 Antibody, C-terminus, intracellular validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using ECL. Rat OATP2 is approximately 75 kD in brain and liver (Noe et al. 1997).

ELISA: 0.5-1.0 μg/mL using 1 μg/mL control peptide per well.

Optimal working dilutions must be determined by the end user.

Physical form

Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Camilla A Thorling et al.
Journal of biomedical optics, 18(10), 101306-101306 (2013-07-03)
The liver is important in the biotransformation of various drugs, where hepatic transporters facilitate uptake and excretion. Ischemia-reperfusion (I/R) injury is a common occurrence in liver surgery, and the developing oxidative stress can lead to graft failure. We used intravital

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