Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.
Specificity
Other species have not been tested.
The antibody reacts with the 29 kDa KLK3 antigen.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.
Application
This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).
Quality
Western Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.
Target description
~31 kDa observed. Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.
Physical form
Format: Purified
Saturated Ammonium Sulfate (SAS)
Storage and Stability
Store at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°
Analysis Note
Control Western Blot : Mouse brain lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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