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8.18887

Sigma-Aldrich

Phloroglucinol

for synthesis

Synonym(s):

Phloroglucinol, 1,3,5-Trihydroxybenzene

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About This Item

Linear Formula:
C6H3-1,3,5-(OH)3
CAS Number:
108-73-6
Molecular Weight:
126.11
MDL number:
MFCD00002286
UNSPSC Code:
12352104
EC Index Number:
203-611-2
NACRES:
NA.22

Quality Level

200

assay

≥99.0% (GC)

form

solid

potency

4000 mg/kg LD50, oral (Rat)

mp

217-220 °C

solubility

10 g/L

bulk density

560 kg/m3

storage temp.

2-30°C

InChI

1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H

InChI key

QCDYQQDYXPDABM-UHFFFAOYSA-N

Application

  • Phloroglucinol in α-glycosidase inhibition: Phloroglucinol derivatives demonstrate effective α-glycosidase inhibitory activity, indicating potential for application in managing diabetes through enzyme inhibition strategies (Sevimli et al., 2024).
  • Phenolic compound bioaccessibility studies: Investigating the intestinal absorption and bioaccessibility of phloroglucinol, among other phenolics, using in vitro simulated gastrointestinal digestion helps understand its pharmacokinetic properties in dietary and pharmaceutical contexts (Pais et al., 2024).
  • Applications in plant biotechnology: Phloroglucinol is utilized in Agrobacterium-mediated transformations, enhancing genetic modification techniques in plant sciences, specifically demonstrated in dwarf soybean transformations (Shao et al., 2024).
  • Methane inhibition studies in dairy cows: Phloroglucinol′s role as a hydrogen acceptor in rumen pulse-dosing experiments demonstrates its potential in reducing methane emissions from dairy cows, contributing to environmental sustainability in agricultural practices (Maigaard et al., 2024).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Identity (IR): passes test

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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