8.07027

1,2-Propylene oxide

for synthesis

• Synonym(s): 1,2-Propylene oxide, 1,2-Epoxypropane, Methyloxirane
• Empirical Formula (Hill Notation): C₃H₆O
• CAS Number: 75-56-9
• Molecular Weight: 58.08
• MDL number: MFCD00005126
• UNSPSC Code: 12352005
• EC Index Number: 200-879-2
• NACRES: NA.22

Properties

• vapor pressure: 585 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥99.0% (GC)
• form: liquid
• autoignition temp.: 430 °C
• potency: 380 mg/kg LD₅₀, oral (Rat); 1245 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.9-36 % (v/v)
• reaction suitability: reaction type: C-C Bond Formation
• kinematic viscosity: 0.37 cSt(20 °C)
• mp: -112 °C
• transition temp: flash point -38 °C
• density: 0.83 g/cm³ at 20 °C
• InChI: 1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3
• InChI key: GOOHAUXETOMSMM-UHFFFAOYSA-N

Description

Application

• Enhanced poly(propylene carbonate) synthesis: Enhanced poly(propylene carbonate) materials were developed through a one-pot synthesis from carbon dioxide, propylene oxide, and a carboxylic dianhydride, showing significant improvements in yield strength when the feed molar ratio of dianhydride to propylene oxide was increased (X Chen et al., 2018).


• Copolymerization with carbon dioxide: A study on the copolymerization and terpolymerization of carbon dioxide/propylene oxide/phthalic anhydride using a cobalt salen complex demonstrated efficient synthesis without forming ether linkages (JY Jeon et al., 2014).


• Polymer architectures: Innovative polymer architectures were explored in the synthesis of poly(ethylene oxide), propylene oxide, and other alkylene oxides, which include novel bioconjugation techniques (J Herzberger et al., 2016).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.828 - 0.832
Identity (IR): passes test

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H224 - H302 - H311 + H331 - H319 - H335 - H340 - H350
• pcodes: P210 - P233 - P280 - P303 + P361 + P353 - P308 + P313 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 1 - Muta. 1B - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: -36.4 °F - Equilibrium method
• flash_point_c: -38 °C - Equilibrium method