679102

Vitamin D₃, 25-Hydroxy-

Metabolite of vitamin D3 via a single cytochrome P450-mediated hydroxylation.

• Synonym(s): Vitamin D₃, 25-Hydroxy-, 25-OH-D₃
• Empirical Formula (Hill Notation): C₂₇H₄₄O₂
• CAS Number: 19356-17-3
• Molecular Weight: 400.64
• MDL number: MFCD00867077
• UNSPSC Code: 12352205
• NACRES: NA.21

Properties

• Quality Level: 100
• assay: ≥99% (LC/MS)
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: ethanol: 10 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
• InChI key: JWUBBDSIWDLEOM-DTOXIADCSA-N

Description

General description

Metabolite of vitamin D₃ via a single cytochrome P450-mediated hydroxylation. Further metabolized to 1α, 25-dihydroxy vitamin D by a second cytochrome P450-mediated hydroxylation. A major circulating metabolite of vitamin D₃.

Metabolite of vitamin D₃ via a single cytochrome P450-mediated hydroxylation. Further metabolized to 1α,2,5-dihydroxy Vitamin D by a second cytochrome P450- mediated-hydroxylation. Major circulating metabolite of vitamin D₃.

Packaging

Packaged under inert gas

Warning

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

Other Notes

DeLuca, H.F., and Schnoes, H.K. 1983. Annu. Rev. Biochem.52, 411.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311,H330,H372
• pcodes: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable