W320307

5-Methylquinoxaline

≥99%, FG

• Synonym(s): Nutty oxaline
• Empirical Formula (Hill Notation): C₉H₈N₂
• CAS Number: 13708-12-8
• Molecular Weight: 144.17
• FEMA Number: 3203
• EC Number: 237-246-5
• Council of Europe no.: 2271
• MDL number: MFCD00012335
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901551
• Flavis number: 14.028
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Fragrance grade; Halal; Kosher
• agency: follows IFRA guidelines; meets purity specifications of JECFA
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FDA 21 CFR 110
• assay: ≥99%
• refractive index: n20/D 1.62 (lit.)
• bp: 120 °C/15 mmHg (lit.)
• mp: 20-21 °C (lit.)
• density: 1.125 g/mL at 25 °C
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• organoleptic: burnt; coffee; corn; nutty; roasted
• SMILES string: Cc1cccc2nccnc12
• InChI: 1S/C9H8N2/c1-7-3-2-4-8-9(7)11-6-5-10-8/h2-6H,1H3
• InChI key: CQLOYHZZZCWHSG-UHFFFAOYSA-N

Description

General description

5-Methylquinoxaline has been identified as one of the key volatile aroma compounds in roasted almonds{170] and roasted coffee.

Application

• Screening of flavor compounds using Ucp1-luciferase reporter beige adipocytes identified 5-methylquinoxaline as a novel UCP1-inducing compound.: This research, published in Bioscience, Biotechnology, and Biochemistry, identifies 5-methylquinoxaline as a novel compound that induces UCP1 in beige adipocytes, suggesting its potential application in metabolic studies and obesity treatment (Kawarasaki et al., 2022).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter