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T32603

Sigma-Aldrich

2-Thiophenecarboxylic acid

ReagentPlus®, 99%

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25 G
$39.70
100 G
$84.10

About This Item

Empirical Formula (Hill Notation):
C5H4O2S
CAS Number:
Molecular Weight:
128.15
Beilstein/REAXYS Number:
110150
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$39.70


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Quality Level

product line

ReagentPlus®

assay

99%

bp

260 °C (lit.)

mp

125-127 °C (lit.)

SMILES string

OC(=O)c1cccs1

InChI

1S/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)

InChI key

QERYCTSHXKAMIS-UHFFFAOYSA-N

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Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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A stereocontrolled synthesis of α-amino-α'-alkoxy ketones is described. This pH-neutral copper(I) thiophene-2-carboxylate (CuTC)-catalyzed cross-coupling of amino acid thiol esters and chiral nonracemic α-alkoxyalkylstannanes gives α-amino-α'-alkoxy ketones in good to excellent yields with complete retention of configuration at the α-amino- and
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In the course of investigating the propensity of aromatic acids to react with selected nucleophiles, we came across an interesting difference in yields for two structurally similar thiophene carboxylic acids. Given that these yields were consistent across more than 40
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