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M50400

Sigma-Aldrich

N-Methylhydroxylamine hydrochloride

98%

Synonym(s):

Methylhydroxylammonium chloride, N-Hydroxy-N-methanamine hydrochloride, N-Hydroxy-N-methylammonium chloride, N-Hydroxymethanamine hydrochloride, N-Hydroxymethylamine hydrochloride, N-Methylhydroxyamine hydrochloride, N-Methylhydroxylamine monohydrochloride, N-Methylhydroxylammonium chloride

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About This Item

Linear Formula:
CH3NHOH · HCl
CAS Number:
4229-44-1
Molecular Weight:
83.52
Beilstein/REAXYS Number:
3541409
EC Number:
224-181-2
MDL number:
MFCD00012597
UNSPSC Code:
12352100
PubChem Substance ID:
24896973
NACRES:
NA.22

Quality Level

200

assay

98%

mp

86-88 °C (lit.)

SMILES string

Cl[H].CNO

InChI

1S/CH5NO.ClH/c1-2-3;/h2-3H,1H3;1H

InChI key

RGZRSLKIOCHTSI-UHFFFAOYSA-N

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Application

Used to construct hydroxamates, important functional groups for the complexation of iron.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Lot/Batch Number
STBL2683
STBK9781
STBJ7422
STBJ7002
STBH4485

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P S Brzović et al.
Biochemistry, 31(4), 1180-1190 (1992-02-04)
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ACS omega, 6(1), 358-366 (2021-01-19)
Doxorubicin (DOX) is widely used to treat solid tumors, but its use is limited by its severe cardiotoxicity, nephrotoxicity, hepatotoxicity, and neurotoxicity. Metabolomic studies on DOX-induced toxicity are mainly focused on alterations in the heart and kidney, but systematic research
S L Martins et al.
European journal of pharmacology, 284(3), 265-270 (1995-09-25)
The effects of the K+ channel blockers, apamin, tetraethylammonium and 4-aminopyridine, upon the relaxations of the isolated rat proximal duodenum induced by nitregic nerve activation, nitric oxide (NO), the NO donor 3-morpholinosydnonimine (SIN-1) and Br-cyclic GMP were determined. The effects
A Gibson et al.
British journal of pharmacology, 96(3), 637-644 (1989-03-01)
1. The effects of N-methylhydroxylamine (NMH) and of M&B 22948 on relaxations of the mouse anococcygeus to non-adrenergic, non-cholinergic (NANC) field stimulation and to a number of smooth muscle relaxant drugs were investigated. 2. Relaxations to NANC field stimulation (10
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