F20807
3-(2-Furyl)acrylic acid
99%
Synonym(s):
Furan-2-acrylic acid, Furfurylideneacetic acid
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C7H6O3
CAS Number:
Molecular Weight:
138.12
Beilstein/REAXYS Number:
81048
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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assay
99%
bp
286 °C (lit.)
mp
139-141 °C (lit.)
SMILES string
OC(=O)\C=C\c1ccco1
InChI
1S/C7H6O3/c8-7(9)4-3-6-2-1-5-10-6/h1-5H,(H,8,9)/b4-3+
InChI key
ZCJLOOJRNPHKAV-ONEGZZNKSA-N
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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P Bünning et al.
Biochemistry, 22(1), 110-116 (1983-01-04)
The angiotensin converting enzyme catalyzed hydrolysis of furanacryloyl-Phe-Gly-Gly is activated by monovalent anions in the order C1- greater than Br- greater than F- greater than NO3- greater than CH3COO-. In the alkaline pH region, increasing anion concentrations decrease the KM
Esters of 2-furanacrylic acid.
P D BARTLETT et al.
Journal of the American Chemical Society, 69(2), 460-460 (1947-02-01)
P Bünning et al.
Biochemistry, 22(1), 103-110 (1983-01-04)
Furanacryloyl-Phe-Gly-Gly has been shown to be a convenient substrate for angiotensin converting enzyme (dipeptidyl carboxypeptidase, EC 3.4.15.1). A detailed kinetic analysis of the hydrolysis of this substrate indicates normal Michaelis-Menten behavior with kcat = 19000 min-1 and KM = 3.0
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