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B22984

Sigma-Aldrich

O-Benzylhydroxylamine hydrochloride

99%

Synonym(s):

Benzyloxyamine hydrochloride

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About This Item

Linear Formula:
C6H5CH2ONH2 · HCl
CAS Number:
2687-43-6
Molecular Weight:
159.61
Beilstein/REAXYS Number:
3687991
EC Number:
220-249-0
MDL number:
MFCD00012952
UNSPSC Code:
12352100
PubChem Substance ID:
24891644
NACRES:
NA.22

assay

99%

form

crystals

mp

238 °C (subl.) (lit.)

SMILES string

Cl.NOCc1ccccc1

InChI

1S/C7H9NO.ClH/c8-9-6-7-4-2-1-3-5-7;/h1-5H,6,8H2;1H

InChI key

HYDZPXNVHXJHBG-UHFFFAOYSA-N

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Application

Effective reagent used to prepare α-hydroxybenzylamines from α-hydroxyketones.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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G Stampf et al.
Die Pharmazie, 35(1), 43-44 (1980-01-01)
The study of the blood levels and tissue concentrations in mice to which 14C-benzyloxyamine hydrochloride was applied in the form of a spray and of a suspensoid aerosol evidenced the good abosrption of this pharmacon. Maximum blood levels were observed
A A Purmal et al.
Mutation research, 364(3), 193-207 (1996-12-02)
Duplex oligonucleotides containing the base lesion analogs, O-methylhydroxylamine- and O-benzylhydroxylamine-modified abasic (AP) sites, were substrates for the DNA N-glycosylases endonuclease III, formamidopyrimidine DNA N-glycosylase and T4 endonuclease V. These N-glycosylases are known to have associated AP lyase activities. In contrast
Tetrahedron Letters, 32, 711-711 (1991)
Yin Luo et al.
ChemMedChem, 7(9), 1587-1593 (2012-07-20)
Forty-three oxime derivatives were synthesized by allowing O-benzylhydroxylamines to react with primary benzaldehydes or salicylaldehydes; these products were gauged as potential inhibitors of β-ketoacyl-(acyl-carrier-protein) synthase III (FabH). Among the 43 compounds, 38 are reported herein for the first time. These
[Thermographic analysis of precipitates formed by the interaction of active ingredients and additives].
G Stampf et al.
Acta pharmaceutica Hungarica, 53(6), 268-272 (1983-11-01)
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