W237507

Diethyl malonate

≥98%, FG

• Synonym(s): Malonic acid diethyl ester
• Linear Formula: CH₂(COOC₂H₅)₂
• CAS Number: 105-53-3
• Molecular Weight: 160.17
• FEMA Number: 2375
• Beilstein/REAXYS Number: 774687
• EC Number: 203-305-9
• Council of Europe no.: 2106
• MDL number: MFCD00009195
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901030
• Flavis number: 9.490
• NACRES: NA.21

Properties

• biological source: synthetic
• grade: FG; Halal
• agency: meets purity specifications of JECFA
• reg. compliance: EU Regulation 1334/2008 & 178/2002; FDA 21 CFR 117; FDA 21 CFR 172.515
• vapor density: 5.52 (vs air)
• vapor pressure: 1 mmHg ( 40 °C)
• assay: ≥98%
• refractive index: n20/D 1.413 (lit.)
• bp: 199 °C (lit.)
• mp: −51-−50 °C (lit.)
• density: 1.055 g/mL at 25 °C (lit.)
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• organoleptic: apple; green; fruity; sweet
• SMILES string: CCOC(=O)CC(=O)OCC
• InChI: 1S/C7H12O4/c1-3-10-6(8)5-7(9)11-4-2/h3-5H2,1-2H3
• InChI key: IYXGSMUGOJNHAZ-UHFFFAOYSA-N

Description

General description

Diethyl malonate is an active methylene compound that can be used as a flavoring agent in the food industry.

Application

• Synthesis and biological activities of novel structural analogues of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.: This study by Suhara et al. focuses on the synthesis of novel structural analogues of 2-arachidonoylglycerol, an endogenous ligand for cannabinoid receptors. The research highlights the utilization of diethyl malonate in the synthesis process, emphasizing its importance in creating biologically active compounds with potential therapeutic applications in modulating cannabinoid receptor activity (Suhara et al., 2001).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 199.4 °F - closed cup
• flash_point_c: 93 °C - closed cup
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)