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861324

Sigma-Aldrich

p-Rosolic acid

Dye content 84 %

Synonym(s):

4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone, Aurin

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25 G
$134.00
100 G
$463.00

About This Item

Empirical Formula (Hill Notation):
C19H14O3
CAS Number:
Molecular Weight:
290.31
Colour Index Number:
43800
Beilstein/REAXYS Number:
2055205
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

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form

powder

Quality Level

composition

Dye content, 84%

technique(s)

titration: suitable

pH

5.0-6.8, yellow to pink

cation traces

C: 66.0-90.8%

λmax

482 nm

ε (extinction coefficient)

≥11000 at 264-270 nm in ethanol
≥50000 at 478-486 nm in ethanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

O=C(C=C1)C=CC1=C(C2=CC=C(O)C=C2)C3=CC=C(O)C=C3

InChI

1S/C19H14O3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20-21H

InChI key

FYEHYMARPSSOBO-UHFFFAOYSA-N

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General description

p-Rosolic acid (C.I. 43800) is an acid-baseindicator from the triphenylmethane group. It is also known as aurin and 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone.

Application

p-Rosolic acid has been used to induce cellular stress in HEK293 cells.[1]

Biochem/physiol Actions

The transition range of p-Rosolic acid is around pH 6.6-8.0 (Below this pH range it is yellow and above it red).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Simultaneous detection of the subcellular localization of RNAs and proteins in cultured cells by combined multicolor RNA-FISH and IF.
Meyer C, et al.
Methods, S1046-2023 (2016)
J Chen et al.
Thrombosis research, 66(2-3), 111-120 (1992-05-01)
To determine whether heparin potentiation of platelet aggregation is related to platelet GP IIb/IIIa and GP Ib receptors, four series of experiments were performed on blood from normal volunteers. In the first experiment pretreatment with the monoclonal antibody 7E3 (MAb
J Balzarini et al.
Biochemical and biophysical research communications, 136(1), 64-71 (1986-04-14)
Aurintricarboxylic acid, an anionic triphenylmethane dye, and Evans Blue, an anionic compound structurally related to suramin, are, like suramin itself, inhibitors of human T-cell lymphotropic virus type III (HTLV-III)/-lymphadenopathy-associated virus (LAV) in vitro. These compounds may be targeted, at least
M Abend et al.
International journal of radiation biology, 75(12), 1567-1578 (2000-01-06)
To investigate the mechanism of micronucleus formation in irradiated L929 cells. Radiation-induced micronuclei (MN) of L929 cells isolated at 48 and 72 h after irradiation were processed for detection of DNA-laddering and higher-order chromatin fragments using conventional gel electrophoresis and
[Not Available].
A DESAUX et al.
Annales de dermatologie et de syphiligraphie, 6(9), 504-504 (1946-09-01)

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