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75950

Sigma-Aldrich

2-Oxovaleric acid

≥98.0% (T)

Synonym(s):

α-Ketovaleric acid, 2-Oxopentanoic acid

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About This Item

Linear Formula:
CH3CH2CH2COCOOH
CAS Number:
Molecular Weight:
116.12
Beilstein/REAXYS Number:
635884
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥98.0% (T)

form

liquid

bp

88-90 °C/12 mmHg (lit.)

mp

7-9 °C (lit.)

density

1.110 g/mL at 20 °C (lit.)

functional group

carboxylic acid
ketone

storage temp.

2-8°C

SMILES string

CCCC(=O)C(O)=O

InChI

1S/C5H8O3/c1-2-3-4(6)5(7)8/h2-3H2,1H3,(H,7,8)

InChI key

KDVFRMMRZOCFLS-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

201.2 °F - closed cup

flash_point_c

94 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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R Bränström et al.
The Journal of biological chemistry, 273(23), 14113-14118 (1998-06-11)
The ATP-regulated potassium (KATP) channel plays an essential role in the control of insulin release from the pancreatic beta-cell. In the present study we have used the patch-clamp technique to study the direct effects of alpha-ketoisocaproate on the KATP channel
T P Healy et al.
Medical and veterinary entomology, 14(2), 195-200 (2000-06-29)
A wind tunnel bioassay and video to observe mosquitoes landing on heated glass cylinders were used to test sweat and some derivatives for responses of Anopheles gambiae Giles (Diptera: Culicidae), a highly anthropophilic African species of malaria vector. Filter papers
C Coronel et al.
Molecular and biochemical parasitology, 4(1-2), 29-38 (1981-11-01)
Whole cell extracts of culture epimastigotes of Trypanosoma cruzi (Tulahuén strain) have alpha-hydroxyacid dehydrogenase activity which catalyzes the NAD-linked reaction alpha-ketoacid in equilibrium with alpha-hydroxyacid, with a variety of substrates. Two molecular forms of the enzyme have been separated by
Z J Wang et al.
Journal of chromatography, 430(2), 223-231 (1988-09-09)
A simple and highly sensitive high-performance liquid chromatographic (HPLC) method for the determination of alpha-keto acids in human serum and urine is described. In an acidic solution, twelve species of alpha-keto acids examined were converted by reaction with 1,2-diamino-4,5-methylenedioxy-benzene into
R Sakowicz et al.
Biochemistry, 32(47), 12730-12735 (1993-11-30)
Threonine 246 is an active site residue that is conserved in all known L-lactate dehydrogenase (LDH; EC 1.1.1.27) sequences. In order to investigate the role of Thr246 in Bacillus stearothermophilus LDH, this residue was altered by site-directed mutagenesis to valine

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