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751480

Sigma-Aldrich

Malonic acid

sublimed grade, ≥99.95% trace metals basis

Synonym(s):

Propanedioic acid

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About This Item

Linear Formula:
CH2(COOH)2
CAS Number:
141-82-2
Molecular Weight:
104.06
Beilstein/REAXYS Number:
1751370
EC Number:
205-503-0
MDL number:
MFCD00002707
UNSPSC Code:
12352300
PubChem Substance ID:
329766221

grade

sublimed grade

assay

≥99.95% trace metals basis

form

powder

mp

132-135 °C (dec.) (lit.)

SMILES string

OC(=O)CC(O)=O

InChI

1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)

InChI key

OFOBLEOULBTSOW-UHFFFAOYSA-N

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General description

The common technique for producing malonic acid is from chloroacetic acid.[1]Malonic acid undergoes thermal decarboxylation at temperatures of 135-137oC.2

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

314.6 °F - closed cup

flash_point_c

157 °C - closed cup

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Certificates of Analysis (COA)

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MKBT3244V
MKBK0990V

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Organic Syntheses, 18, 50-50 (1938)
E A Haan et al.
European journal of pediatrics, 144(6), 567-570 (1986-04-01)
A second child with a more severe deficiency of malonyl CoA decarboxylase is described. He is mildly mentally retarded and presented with vomiting, a seizure, hypoglycaemia and mild metabolic acidosis during a urinary tract infection. The urine contained increased amounts
Bogdan Belgorodsky et al.
Bioconjugate chemistry, 16(5), 1058-1062 (2005-09-22)
The preparation and characterization of the stable human serum albumin (HSA)-C3 isomer of tris-malonic acid [C60]fullerene complex is reported. Other than the anti-fullerene antibody, a stable protein-fullerene complex with a native protein has never been observed. This study may provide
Anna Shevchenko et al.
International journal of pharmaceutics, 436(1-2), 403-409 (2012-07-04)
Cocrystallization and salt formation have been shown to entail substantial promise in tailoring the physicochemical properties of drug compounds, in particular, their dissolution and hygroscopicity. In this work, we report on the preparation and comparative evaluation of a new cocrystal
Matthias Bauwens et al.
PloS one, 7(6), e38428-e38428 (2012-06-22)
In vivo pH imaging has been a field of interest for molecular imaging for many years. This is especially important for determining tumor acidity, an important driving force of tumor invasion and metastasis formation, but also in the process of
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