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71868

Sigma-Aldrich

1-(4-Methylphenyl)piperazine

≥98.0%

Synonym(s):

1-(p-Tolyl)piperazine

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About This Item

Empirical Formula (Hill Notation):
C11H16N2
CAS Number:
Molecular Weight:
176.26
Beilstein/REAXYS Number:
139489
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

≥98.0%

form

crystals

mp

29-32 °C

SMILES string

Cc1ccc(cc1)N2CCNCC2

InChI

1S/C11H16N2/c1-10-2-4-11(5-3-10)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3

InChI key

ONEYFZXGNFNRJH-UHFFFAOYSA-N

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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V Stuettgen et al.
The AAPS journal, 22(2), 33-33 (2020-01-29)
A limiting factor for oral delivery of macromolecules is low intestinal epithelial permeability. 1-Phenylpiperazine (PPZ), 1-(4-methylphenyl) piperazine (1-4-MPPZ) and 1-methyl-4-phenylpiperazine (1-M-4-PPZ) have emerged as potential permeation enhancers (PEs) from a screen carried out by others in Caco-2 monolayers. Here, their

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