668265

N-Boc-2-piperidineethanol

97%

• Synonym(s): 1-tert-Butoxycarbonyl-2-piperidineethanol, 2-(2-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester, N-Boc-2-(2-hydroxymethyl)piperidine
• Empirical Formula (Hill Notation): C₁₂H₂₃NO₃
• CAS Number: 118811-03-3
• Molecular Weight: 229.32
• MDL number: MFCD03701252
• UNSPSC Code: 12352100
• PubChem Substance ID: 24884972
• NACRES: NA.22

Properties

• assay: 97%
• refractive index: n20/D 1.472
• bp: 100-110 °C/0.3 mmHg
• density: 1.032 g/mL at 25 °C
• functional group: hydroxyl
• SMILES string: CC(C)(C)OC(=O)N1CCCCC1CCO
• InChI: 1S/C12H23NO3/c1-12(2,3)16-11(15)13-8-5-4-6-10(13)7-9-14/h10,14H,4-9H2,1-3H3
• InChI key: LTVQOFUGXMVESU-UHFFFAOYSA-N

Description

Application

Reactant for synthesis of:

• Vasopressin1b receptor antagonists
• CXCR4 antagonists as anti-HIV agents
• Coumarin-based inhibitors of inducible nitric oxide synthase
• Selective thrombin inhibitors

Reactant for:

• N-directed hydroboration for synthesis of amino alcohols
• Enantioselective synthesis of sedamine and allosedamine

Safety Information

• pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H301,H400
• pcodes: P273 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: >230.0 °F
• flash_point_c: > 110 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter