655872

N-Boc-piperidine

98%

• Synonym(s): 1-Boc-piperidine, N-(tert-Butoxycarbonyl)piperidine, N-Boc-tetrahydropyridine
• Empirical Formula (Hill Notation): C₁₀H₁₉NO₂
• CAS Number: 75844-69-8
• Molecular Weight: 185.26
• MDL number: MFCD02093935
• UNSPSC Code: 12352100
• PubChem Substance ID: 24884129

Properties

• assay: 98%
• refractive index: n20/D 1.454 (lit.)
• density: 0.964 g/mL at 25 °C (lit.)
• SMILES string: CC(C)(C)OC(=O)N1CCCCC1
• InChI: 1S/C10H19NO2/c1-10(2,3)13-9(12)11-7-5-4-6-8-11/h4-8H2,1-3H3
• InChI key: RQCNHUCCQJMSRG-UHFFFAOYSA-N

Description

Application

Reactant for synthesis of:

• Piperazine derivatives for orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors
• 2-Aryl and 2-vinyl piperidines
• Allosteric IGF-1R inhibitors

Reactant for:

• Allylation and conjugate addition reactions
• Asymmetric deprotonation
• Enantioselective inter- and intramolecular aldol reactions

Substrate used in a two-step α-arylation procedure.

Safety Information

• pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H301,H315,H319,H335,H400
• pcodes: P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: 186.8 °F - closed cup
• flash_point_c: 86 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter