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About This Item
Linear Formula:
17O2
CAS Number:
Molecular Weight:
34.00
MDL number:
UNSPSC Code:
12142200
PubChem Substance ID:
Note: This product can be packaged on demand. For information on pricing, availability and packaging of custom sizes, please contact Stable Isotopes Customer Service
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isotopic purity
90 atom % 17O
assay
99% (CP)
form
gas
mass shift
M+2
SMILES string
[17O]=[17O]
InChI
1S/O2/c1-2/i1+1,2+1
InChI key
MYMOFIZGZYHOMD-ZDOIIHCHSA-N
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General description
Oxygen-17O2 is the isotopic analogue of oxygen.
Application
Oxygen-17O2 can be used
to estimate the cerebral metabolic rate of oxygen consumption (CMRO2) of swine by detection of metabolically produced H217O by rapid T1-weighted proton magnetic resonance imaging.
to understand the altered cerebral oxygen metabolism in glioma via dynamic 17O MRI.
to measure the quantitative and simultaneous measurement of oxygen consumption rates in rat brain and skeletal muscle using 17O MRS imaging.
to estimate the cerebral metabolic rate of oxygen consumption (CMRO2) of swine by detection of metabolically produced H217O by rapid T1-weighted proton magnetic resonance imaging.
to understand the altered cerebral oxygen metabolism in glioma via dynamic 17O MRI.
to measure the quantitative and simultaneous measurement of oxygen consumption rates in rat brain and skeletal muscle using 17O MRS imaging.
Packaging
All gas volumes are quoted at Standard Temperature and Pressure (STP) and not at Normal Temperature and Pressure (NTP). One STP Liter is 7.7% more gas than one NTP Liter.
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
signalword
Danger
hcodes
Hazard Classifications
Ox. Gas 1 - Press. Gas Compr. Gas
Storage Class
2A - Gases
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Daniel Paech et al.
Radiology, 295(1), 181-189 (2020-02-19)
Background Altered metabolism is a characteristic of cancer. Because of a shift in glucose metabolism from oxidative phosphorylation to lactate production for energy generation, malignant tumors are characterized by increased glycolysis followed by lactic acid fermentation, even in the presence
Hannes M Wiesner et al.
Magnetic resonance in medicine, 85(4), 2232-2246 (2020-10-27)
Oxygen-17 (17 O) MRS imaging, successfully used in the brain, is extended by imaging the oxygen metabolic rate in the resting skeletal muscle and used to determine the total whole-body oxygen metabolic rate in the rat. During and after inhalations
Eric A Mellon et al.
Journal of neuroscience methods, 179(1), 29-39 (2009-05-12)
Despite the importance of metabolic disturbances in many diseases, there are currently no clinically used methods for the detection of oxidative metabolism in vivo. To address this deficiency, (17)O MRI techniques are scaled from small animals to swine as a
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