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Sigma-Aldrich

2-Hydroxyethylhydrazine

≥95% (GC)

Synonym(s):

2-Hydrazinoethanol

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About This Item

Linear Formula:
HOCH2CH2NHNH2
CAS Number:
109-84-2
Molecular Weight:
76.10
Beilstein/REAXYS Number:
1731669
EC Number:
203-711-6
MDL number:
MFCD00007623
UNSPSC Code:
12352100
PubChem Substance ID:
57651467
NACRES:
NA.22

assay

≥95% (GC)

refractive index

n20/D 1.493 (lit.)
n20/D 1.493

bp

155-160 °C/32 mmHg (lit.)

mp

−70 °C (lit.)

density

1.123 g/mL at 25 °C (lit.)

SMILES string

NNCCO

InChI

1S/C2H8N2O/c3-4-1-2-5/h4-5H,1-3H2

InChI key

GBHCABUWWQUMAJ-UHFFFAOYSA-N

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General description

2-Hydroxyethylhydrazine reacts with β-diketones having strong electron-withdrawing substituents to yield 5-hydroxy-4,5-dihydropyrazoles.

Other Notes

Sales restrictions may apply

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

170.6 °F - closed cup

flash_point_c

77 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phenylhydrazine 97%

Sigma-Aldrich

P26252

Phenylhydrazine

Hydrazine monohydrate N2H4 64-65 %, reagent grade, ≥97%

Sigma-Aldrich

207942

Hydrazine monohydrate

Reaction of 2-hydroxyethylhydrazine with a trifluoromethyl-?-diketone: Study and structural characterization of a new 5-hydroxy-5-trifluoromethyl-4, 5-dihydropyrazole intermediate.
Montoya V, et al.
Journal of Fluorine Chemistry, 128(9), 1007-1011 (2007)
Smaail Radi et al.
Molecules (Basel, Switzerland), 21(8), doi:10-doi:10 (2016-08-17)
A pyridylpyrazole bearing a hydroxyethyl substituent group has been synthesized by condensation of (Z)-4-hydroxy-4-(pyridin-2-yl)but-3-en-2-one with 2-hydroxyethylhydrazine. The compound was well characterized and its structure confirmed by single crystal X-ray diffraction. Density functional calculations have been performed using DFT method with
Gregory M Sandala et al.
Journal of the American Chemical Society, 127(24), 8856-8864 (2005-06-16)
Ab initio molecular orbital calculations have been used to study the mechanism of suicide inactivation of ethanolamine ammonia-lyase induced by three different substrate analogues. Analysis of the normal catalytic mechanism with 2-aminoethanol (ethanolamine) as substrate predicts that both the hydrogen-abstraction
A M Timperio et al.
Xenobiotica; the fate of foreign compounds in biological systems, 33(2), 153-167 (2003-03-08)
1 Furazolidone, a drug widely used in human and veterinary medicine, exhibits inhibition of monoamine oxidase activity, as observed in the tissues of a number of different animal species, including man. The aim of the current study was to determine
R D Slocum et al.
Planta, 183(3), 443-450 (1991-02-01)
An electron-microscopic cytochemical method was used to localize diamine oxidase (DAO) in pea and polyamine oxidase (PAO) in maize (Zea mays L.). The method, based on the precipitation of amine-oxidase-generated H2O2 by CeCl3, was shown to be specific for DAO
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