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543136

Sigma-Aldrich

Propargyl acrylate

98%

Synonym(s):

Acrylic acid propargyl ester

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About This Item

Linear Formula:
CH2=CHCO2CH2C≡CH
CAS Number:
10477-47-1
Molecular Weight:
110.11
EC Number:
233-975-8
MDL number:
MFCD00078451
UNSPSC Code:
12352100
PubChem Substance ID:
24878664
NACRES:
NA.22

Quality Level

100

assay

98%

contains

200 ppm BHT as inhibitor

refractive index

n20/D 1.447 (lit.)

bp

142-143 °C (lit.)

density

0.997 g/mL at 25 °C (lit.)

SMILES string

C=CC(=O)OCC#C

InChI

1S/C6H6O2/c1-3-5-8-6(7)4-2/h1,4H,2,5H2

InChI key

WPBNLDNIZUGLJL-UHFFFAOYSA-N

General description

Propargyl acrylate is a propargyl ester of acrylic acid. It participates in the preparation of lipid nanoparticles for use in siRNA delivery.

Application

Propargyl acrylate may be used to synthesize:
  • linear poly(N-isopropylacrylamide)(PNIPAM)
  • 1-[3-(2-methyl-2-dodecylsulfanylthiocarbonylsulfanylpropionyloxy)propyl]-1H-[1,2,3]triazol-4-ylmethyl acrylate, an acryloyl trithiocarbonate chain transfer agent
  • propranolol-imprinted core–shell nanoparticles (mipCS)

Pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

109.9 °F - closed cup

flash_point_c

43.3 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Andreas Hoffmann et al.
Journal of tissue engineering, 8, 2041731417744485-2041731417744485 (2018-01-11)
Stereolithography is one of the most promising technologies for the production of tailored implants. Within this study, we show the results of a new resin formulation for three-dimensional printing which is also useful for subsequent surface functionalization. The class of
Temperature-induced phase transition of well-defined cyclic poly (N-isopropylacrylamide) s in aqueous solution
Qiu X-P, et al.
Macromolecules, 40.20, 7069- 7071 (2007)
Guang Huang et al.
Journal of separation science, 39(8), 1461-1470 (2016-02-26)
A novel silica-based stationary phase with branched octadecyl groups was prepared by the sequential employment of the Michael addition reaction and photoinduced thiol-yne click chemistry with 3-aminopropyl-functionalized silica microspheres as the initial material. The resulting stationary phase denoted as SiO2
Molecularly imprinted magnetic materials prepared from modular and clickable nanoparticles
Xu C, et al.
Journal of Materials Chemistry, 22.15, 7427-7433 (2012)
Hyperbranched polymers via RAFT copolymerization of an acryloyl trithiocarbonate
Vogt AP, et al.
Australian Journal of Chemistry, 60.6, 396-399 (2007)
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