536954

Rosmarinic acid

96%

• Synonym(s): (R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester
• Empirical Formula (Hill Notation): C₁₈H₁₆O₈
• CAS Number: 20283-92-5
• Molecular Weight: 360.31
• Beilstein/REAXYS Number: 2227587
• MDL number: MFCD00017740
• UNSPSC Code: 12352106
• PubChem Substance ID: 24878185
• NACRES: NA.22

Properties

• assay: 96%
• form: powder
• mp: 171-175 °C (lit.)
• SMILES string: OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2
• InChI: 1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
• InChI key: DOUMFZQKYFQNTF-WUTVXBCWSA-N
• Gene Information: human ... LCK(3932)

Description

General description

Rosmarinic acid is a bioactive plant phenolic compound with antioxidant and anti-inflammatory effects.

Application

Rosmarinic acid has been used as a model compound to study its biological effects in animal models. Various studies have shown its ability to:

• Inhibit nephropathy.
• Inhibit gentamicin sulfate (GS)-induced renal oxidative damage.
• Reduce noise-induced hearing loss.
• Reduce depression.
• Reduce post-traumatic stress disorder (PTSD)-like symptoms.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)