515213

Methyl 3-indoleglyoxylate

98%

• Synonym(s): Methyl 2-(indol-3-yl)-2-oxoacetate
• Empirical Formula (Hill Notation): C₁₁H₉NO₃
• CAS Number: 18372-22-0
• Molecular Weight: 203.19
• MDL number: MFCD00047173
• UNSPSC Code: 12352100
• PubChem Substance ID: 24873805
• NACRES: NA.22

Properties

• assay: 98%
• mp: 227-230 °C (lit.)
• SMILES string: COC(=O)C(=O)c1c[nH]c2ccccc12
• InChI: 1S/C11H9NO3/c1-15-11(14)10(13)8-6-12-9-5-3-2-4-7(8)9/h2-6,12H,1H3
• InChI key: VFIJGAWYVXDYLK-UHFFFAOYSA-N

Description

Application

• Reactant for preparation of sotrastaurin analogs as protein kinase inhibitors
• Reactant for synthesis of GSK-3 inhibitors
• Reactant for Diels-Alder cycloaddition
• Reactant for preparation of a Janus kinase 3 inhibitor
• Reactant for synthesis of cephalandole alkaloids
• Reactant for stereoselective preparation of COX-2 inhibitor as anticancer agent
• Reactant for synthesis of cycloalkene indole carbazole alkaloids via ring-closing metathesis

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves