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49560

Sigma-Aldrich

L-Glutamic acid dimethyl ester hydrochloride

≥99.0% (anhydrous basis material, AT)

Synonym(s):

L-Glu(OMe)OMe·HCl

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10 G
$94.90
50 G
$212.10

$94.90

Available to ship onApril 29, 2025Details

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10 G
$94.90
50 G
$212.10

About This Item

Linear Formula:
CH3COOCH2CH2CH(NH2)COOCH3 · HCl
CAS Number:
23150-65-4
Molecular Weight:
211.64
Beilstein/REAXYS Number:
4238829
EC Number:
245-461-0
MDL number:
MFCD00038879
UNSPSC Code:
12352209
PubChem Substance ID:
57651206
NACRES:
NA.22

$94.90

Available to ship onApril 29, 2025Details

Request a Bulk Order

Quality Level

100

assay

≥99.0% (anhydrous basis material, AT)

optical activity

[α]20/D +26.0±1°, c = 5% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

impurities

~2% water

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cl.COC(=O)CC[C@H](N)C(=O)OC

InChI

1S/C7H13NO4.ClH/c1-11-6(9)4-3-5(8)7(10)12-2;/h5H,3-4,8H2,1-2H3;1H/t5-;/m0./s1

InChI key

MFUPLHQOVIUESQ-JEDNCBNOSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH8554
BCCF6012
BCCF4680
BCBL2664V
BCBG6768V

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A Sener et al.
The American journal of physiology, 267(4 Pt 1), E573-E584 (1994-10-01)
Glutamic acid dimethyl ester (GME; 3.0-10.0 mM) enhanced insulin release evoked by 6.0-8.3 mM D-glucose, 1.0-10.0 mM L-leucine, or 5.0-10.0 mM 2-amino-bicyclo(2,2,1)heptane-2-carboxylic acid, causing a shift to the left of the sigmoidal relationship between insulin output and D-glucose concentration. In
T M Zhang et al.
The American journal of physiology, 270(5 Pt 1), G852-G859 (1996-05-01)
The dimethyl esters of succinic acid (SAD) and glutamic acid (GME) were found to be efficiently metabolized in colon carcinoma cells of the Caco-2 line. The rate of [1,4-14C]SAD and [2,3-14C]SAD conversion to radioactive acidic metabolites, CO2, amino acids, pyruvic
J Rasschaert et al.
Journal of molecular endocrinology, 13(2), 209-217 (1994-10-01)
This study aimed to compare the metabolic and secretory responses of pancreatic islets from animals with non-insulin-dependent diabetes to D-glucose with the effects of the methyl esters of succinic acid (SME) and glutamic acid (GME). The insulin secretory response to
G N Akoev et al.
Neirofiziologiia = Neurophysiology, 20(4), 457-463 (1988-01-01)
Ampullae of Lorenzini isolated from the skate (Raja clavata) have been investigated in vitro electrophysiologically to determine the nature of the transmitter at the synapse between the electroreceptor cells and afferent fibres. Glutamic acid diethyl ester (GDEE), glutamic acid dimethyl
M Joëls et al.
Experimental brain research, 54(3), 455-462 (1984-01-01)
Electrical stimulation of fimbria-fornix (fi-fx) fibers monosynaptically activated many of the neurons tested in the lateral septal complex (LSC) of the rat. The orthodromically activated LSC neurons were classified as "strongly" orthodromically activated (SOA) or "weakly" orthodromically activated ( WOA
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