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Key Documents

465887

Sigma-Aldrich

trans-3,5-Bis(trifluoromethyl)cinnamic acid

98%

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About This Item

Linear Formula:
(CF3)2C6H3CH=CHCO2H
CAS Number:
Molecular Weight:
284.15
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

form

solid

mp

166-169 °C (lit.)

SMILES string

[H]\C(=C(\[H])c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(O)=O

InChI

1S/C11H6F6O2/c12-10(13,14)7-3-6(1-2-9(18)19)4-8(5-7)11(15,16)17/h1-5H,(H,18,19)/b2-1+

InChI key

IZKCKOPHMWHBHR-OWOJBTEDSA-N

Application

trans-3,5-Bis(trifluoromethyl)cinnamic acid (F-CIN) was employed as hydrophobic probe to investigate the interactions between hydrophobic guest molecules and polymers forming the micelle core.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Cristiano Giacomelli et al.
Langmuir : the ACS journal of surfaces and colloids, 23(13), 6947-6955 (2007-05-26)
Block copolymer micelles find application in many fields as nanocarriers, especially in drug delivery. We report herein that specific interactions between hydrophobic guest molecules and core-forming segments can significantly improve the loading capacity of polymeric micelles. High loading capacities (>100%

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