Skip to Content
MilliporeSigma
All Photos(2)

Documents

412201

Sigma-Aldrich

L-Serine methyl ester hydrochloride

98%, for peptide synthesis

Synonym(s):

L-Serine methyl ester·HCl

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
HOCH2CH(NH2)COOCH3 · HCl
CAS Number:
5680-80-8
Molecular Weight:
155.58
Beilstein/REAXYS Number:
3559591
EC Number:
227-140-7
MDL number:
MFCD00063680
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24865794
NACRES:
NA.22

product name

L-Serine methyl ester hydrochloride, 98%

assay

98%

form

powder

optical activity

[α]20/D +3.4°, c = 4 in methanol

reaction suitability

reaction type: solution phase peptide synthesis

mp

163 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Cl.COC(=O)[C@@H](N)CO

InChI

1S/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H/t3-;/m0./s1

InChI key

NDBQJIBNNUJNHA-DFWYDOINSA-N

Looking for similar products? Visit Product Comparison Guide

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

L-Cysteine methyl ester hydrochloride 98%

Sigma-Aldrich

410209

L-Cysteine methyl ester hydrochloride

J Sélambarom et al.
Carbohydrate research, 330(1), 43-51 (2001-02-24)
The reaction of L-serine methyl ester hydrochloride (1) with paraformaldehyde (2) in dichloromethane in the presence of triethylamine afforded a novel compound: [lS,2S,6S,7S]-1,6-diaza-4,9-dioxa-2,7-dimethoxycarbonylbicyclo[4.4.1]undecane (4) as a 2:3 adduct of 1 with 2. 1H and 13C NMR spectroscopy were unable to
Cédric Couturier et al.
Organic letters, 8(10), 2183-2186 (2006-05-05)
[reaction: see text] Reaction of N,N-dibenzyl-O-methylsulfonyl serine methyl ester with a variety of heteronucleophiles (sodium azide, sodium phthalimide, amines, thiols) and carbanions (sodium malonate) gave, via an aziridinium intermediate, the corresponding beta-amino or alpha,beta-diamino ester in good to excellent yield.
Yu Harayama et al.
Chemical communications (Cambridge, England), (13)(13), 1764-1766 (2005-03-26)
The use of hypervalent iodine(III) reagents allowed us to develop the novel and efficient direct synthesis of N,O-acetal compounds via the oxidative fragmentation reaction of alpha-amino acids or alpha-amino alcohols; furthermore, we succeeded in developing an improved synthesis of the
Carlos Aydillo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(17), 4840-4848 (2007-03-17)
A new chiral serine equivalent and its enantiomer have been synthesized from (S)- and (R)-N-Boc-serine methyl esters (Boc: tert-butyloxycarbonyl). The use of these compounds as chiral building blocks has been demonstrated in the synthesis of alpha-alkyl alpha-amino acids by diastereoselective
Ernest Mordret et al.
Molecular cell, 75(3), 427-441 (2019-07-30)
The translation machinery and the genes it decodes co-evolved to achieve production throughput and accuracy. Nonetheless, translation errors are frequent, and they affect physiology and protein evolution. Mapping translation errors in proteomes and understanding their causes is hindered by lack
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service