410438

Methyl (S)-(−)-3-Boc-2,2-dimethyl-4-oxazolidinecarboxylate

98%

• Synonym(s): Methyl (S)-(−)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-oxazolidinecarboxylate
• Empirical Formula (Hill Notation): C₁₂H₂₁NO₅
• CAS Number: 108149-60-6
• Molecular Weight: 259.30
• MDL number: MFCD00192279
• UNSPSC Code: 12352005
• PubChem Substance ID: 24865525
• NACRES: NA.22

Properties

• assay: 98%
• form: liquid
• optical activity: [α]20/D −55°, c = 1.3 in chloroform
• optical purity: ee: 99% (HPLC)
• refractive index: n20/D 1.443 (lit.)
• bp: 101-102 °C/2 mmHg (lit.)
• density: 1.082 g/mL at 25 °C (lit.)
• functional group: ester; ether
• SMILES string: COC(=O)[C@@H]1COC(C)(C)N1C(=O)OC(C)(C)C
• InChI: 1S/C12H21NO5/c1-11(2,3)18-10(15)13-8(9(14)16-6)7-17-12(13,4)5/h8H,7H2,1-6H3/t8-/m0/s1
• InChI key: ZNBUXTFASGDVCL-QMMMGPOBSA-N

Description

Application

Precursor to a configurationally stable serinal derivative (Garner′s aldehyde) that has been used to make azasugars, sphingolipids, and the amino sugar found in calicheamicin, a potent antitumor agent.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 199.4 °F - closed cup
• flash_point_c: 93 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter