Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

390755

Sigma-Aldrich

Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate

97%

Synonym(s):

Difluoro(fluorosulfonyl)acetic acid methyl ester

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
FSO2CF2CO2CH3
CAS Number:
680-15-9
Molecular Weight:
192.11
Beilstein/REAXYS Number:
1812896
MDL number:
MFCD00144316
UNSPSC Code:
12352100
PubChem Substance ID:
24864345
NACRES:
NA.22

assay

97%

form

liquid

reaction suitability

reaction type: click chemistry

refractive index

n20/D 1.351 (lit.)

bp

117-118 °C (lit.)

density

1.509 g/mL at 25 °C (lit.)

functional group

ester
fluoro

SMILES string

COC(=O)C(F)(F)S(F)(=O)=O

InChI

1S/C3H3F3O4S/c1-10-2(7)3(4,5)11(6,8)9/h1H3

InChI key

GQJCAQADCPTHKN-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

  • Useful reagent for the trifluoromethylation of alkyl halides.
  • Broadly applicable reagent for perfluoroalkylations for aryl iodides and bromides

pictograms

FlameCorrosion
GHS02,GHS05

signalword

Danger

hcodes

H226,H314

Hazard Classifications

Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

116.6 °F - closed cup

flash_point_c

47 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCX0657
MKCW0743
MKCR4523
MKCN2858
MKCM1700

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Journal of the Chemical Society. Chemical Communications, 705-705 (1989)
A broadly applicable copper reagent for trifluoromethylations and perfluoroalkylations of aryl iodides and bromides.
Hiroyuki Morimoto et al.
Angewandte Chemie (International ed. in English), 50(16), 3793-3798 (2011-03-29)
David Orr et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 20(44), 14305-14316 (2014-09-13)
Vinyl cyclopropane rearrangement (VCPR) has been utilised to synthesise a difluorinated cyclopentene stereospecifically and under mild thermal conditions. Difluorocyclopropanation chemistry afforded ethyl 3-(1'(2'2'-difluoro-3'-phenyl)cyclopropyl) propenoate as all four stereoisomers (18a, 18b, 22a, 22b) (all racemic). The trans-E isomer (18a), prepared in

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service