359955

Boron trifluoride acetic acid complex

98%

• Synonym(s): Boron trifluoride-acetic acid (1:2)
• Linear Formula: BF₃ · 2CH₃COOH
• CAS Number: 373-61-5
• Molecular Weight: 187.91
• Beilstein/REAXYS Number: 3686517
• EC Number: 206-768-5
• MDL number: MFCD00036359
• UNSPSC Code: 12352106
• PubChem Substance ID: 24862129
• NACRES: NA.22

Properties

• assay: 98%
• form: liquid
• reaction suitability: core: boron; reagent type: catalyst
• refractive index: n20/D 1.368 (lit.)
• density: 1.353 g/mL at 25 °C (lit.)
• SMILES string: CC(O)=O.CC(O)=O.FB(F)F
• InChI: 1S/2C2H4O2.BF3/c2*1-2(3)4;2-1(3)4/h2*1H3,(H,3,4);
• InChI key: COTMJGCQSLZICX-UHFFFAOYSA-N

Description

General description

Boron trifluoride acetic acid is a versatile Lewis acid catalyst in organic synthesis with various applications. It is used as a catalyst in various reactions such as esterification, Friedel-Crafts reactions, oxidation, Fries rearrangement, and polymerization reactions.

Application

Boron trifluoride acetic acid complex is used as a Lewis acid catalyst in the Fries rearrangement reaction, which is a critical step in the total synthesis of furanaphin. It is also used as a co-catalyst in the intramolecular amination reaction of primary sulfonamides to form cyclic carbamates.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314
• pcodes: P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Acute Tox. 4 Oral - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 181.4 °F - closed cup
• flash_point_c: 83 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter