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357871

Sigma-Aldrich

5-Mercapto-1-methyltetrazole

98%

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About This Item

Empirical Formula (Hill Notation):
C2H4N4S
CAS Number:
Molecular Weight:
116.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

form

powder

mp

125-128 °C (lit.)

SMILES string

Cn1nnnc1S

InChI

1S/C2H4N4S/c1-6-2(7)3-4-5-6/h1H3,(H,3,5,7)

Inchi Key

XOHZHMUQBFJTNH-UHFFFAOYSA-N

General description

5-Mercapto-1-methyltetrazole is a heterocyclic thiol derivative. It forms dimeric or tetrameric complexes with trimethylgallium.

Application

5-Mercapto-1-methyltetrazole may be employed as heterocyclic ligand to study the geometry and stereochemical activity of the lone pair at the lead atom in hemi- and holo-directed lead(II) complexes. It may be used in the chemical modification of submicron particles of mesoporous MSU-2 silica and SBA-15 mesoporous silica.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1A - Other explosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N Kanazumi et al.
Hepato-gastroenterology, 47(36), 1695-1699 (2001-01-10)
In this study, we examined the influence of clinical treatments in the perioperative period upon PIVKA-II (plasma levels of protein induced by vitamin K absence or antagonist-II) in patients with hepatocellular carcinoma and pancreatobiliary diseases. During a perioperative period, plasma
K Kawamoto et al.
Japanese journal of pharmacology, 47(2), 169-178 (1988-06-01)
Liver microsomal vitamin K epoxide reductase activity was determined by measuring the formation of menaquinone-4 from the substrate menaquinone-4 2,3-epoxide. The enzyme was active when dithiothreitol (DTT) was used as a reducing agent, and the activity increased gradually with increasing
K Kawamoto et al.
Japanese journal of pharmacology, 50(2), 159-165 (1989-06-01)
NADH-dependent vitamin K reductase activity in rat liver microsomes was measured by detecting the amount of the reduced form of vitamin K from the oxidized form of the vitamin. The enzyme activity was not detected when intact microsomes were employed
Damián Pérez-Quintanilla et al.
Journal of nanoscience and nanotechnology, 9(8), 4901-4909 (2009-11-26)
Submicron particles of mesoporous MSU-2 silica have been obtained by using Tergitol NP-9 as nonionic surfactant and TEOS as silica precursor. The material has been chemically modified with 5-mercapto-1-methyltetrazole and characterized by powder X-ray diffraction, TEM, SEM, N2 adsorption, FT-IR
J J Lipsky
Biochemical pharmacology, 38(5), 773-779 (1989-03-01)
Antibiotics that contain the 1-methyltetrazole-5-thiol (MTT) leaving group are associated with an adverse effect when alcohol is ingested after their administration. Therefore, the ability of MTT to inhibit an enzyme in alcohol metabolism, aldehyde dehydrogenase (ALDH), was examined. In the

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