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284025

Sigma-Aldrich

Diethylenetriaminepentaacetic dianhydride

98%

Synonym(s):

N,N-Bis[2-(2,6-dioxomorpholino)ethyl]glycine, DTPA anhydride, DTPA dianhydride

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O8
CAS Number:
23911-26-4
Molecular Weight:
357.32
Beilstein/REAXYS Number:
1230954
MDL number:
MFCD00010697
UNSPSC Code:
12162002
PubChem Substance ID:
24857140
NACRES:
NA.23

Quality Level

200

assay

98%

form

powder

mp

182-184 °C (lit.)

storage temp.

−20°C

SMILES string

OC(=O)CN(CCN1CC(=O)OC(=O)C1)CCN2CC(=O)OC(=O)C2

InChI

1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)

InChI key

RAZLJUXJEOEYAM-UHFFFAOYSA-N

Related Categories

Application

Employed in the synthesis of macrocyclic ligands and lanthanide complexes that are useful as MRI enhancers.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000407142
0000407142
0000310590
0000261577
SLCF1763

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Farid N Faruqu et al.
Theranostics, 9(6), 1666-1682 (2019-05-01)
Extracellular vesicles, in particular exosomes, have recently gained interest as novel drug delivery vectors due to their biological origin and inherent intercellular biomolecule delivery capability. An in-depth knowledge of their in vivo biodistribution is therefore essential. This work aimed to
Inorganic Chemistry, 33, 5794-5794 (1994)
Yongbo Yang et al.
ACS applied materials & interfaces, 9(28), 23450-23457 (2017-06-29)
A bimodal contrast nanoagent was developed by chelating gadolinium ions to 2-[bis[2-[carboxymethyl-[2-oxo-2-(2-sulfanylethyl-amino)ethyl]amino]ethyl]amino]acetic acid (DTDTPA)-modified CuInS
C H Paik et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 24(12), 1158-1163 (1983-12-01)
Diethylenetriaminepentaacetic acid (DTPA) was conjugated with a practical concentration (300 micrograms/ml) of antibody to human albumin (Ab) and 1083 17-1A monoclonal colorectal antibody (MAb-17-1A) via an acylation reaction using cyclic DTPA anhydride (cDTPAA). The conjugation reaction was favored as pH
B M Kinsey et al.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 15(3), 285-292 (1988-01-01)
We have developed a simple, rapid, and reproducible method for conjugating the bifunctional metal chelator diethylenetriaminepentaacetic acid (DTPA) to an IgM monoclonal antibody (MoAb) without first isolating the MoAb from the ascites fluid. Treatment of the protein mixture in the
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