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270369

Supelco

1,1,2-Trichlorotrifluoroethane

HPLC grade, ≥99.9%

Synonym(s):

1,1,2-Trichloro-1,2,2-trifluoroethane, 1,1,2-Trichloro-trifluoroethane, Genetron® 113

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About This Item

Linear Formula:
ClCF2CCl2F
CAS Number:
76-13-1
Molecular Weight:
187.38
Beilstein/REAXYS Number:
1740335
EC Number:
200-936-1
MDL number:
MFCD00000782
UNSPSC Code:
12190000
PubChem Substance ID:
329752932

grade

HPLC grade

vapor density

6.5 (vs air)

vapor pressure

5.5 psi ( 20 °C)

assay

≥99.9%

form

liquid

autoignition temp.

1256 °F

technique(s)

HPLC: suitable

impurities

<0.010% water

evapn. residue

<0.0005%

refractive index

n20/D 1.358 (lit.)

bp

47-48 °C (lit.)

mp

−35 °C (lit.)

density

1.57 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 231 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 260-400 nm Amax: 0.01

SMILES string

FC(F)(Cl)C(F)(Cl)Cl

InChI

1S/C2Cl3F3/c3-1(4,6)2(5,7)8

InChI key

AJDIZQLSFPQPEY-UHFFFAOYSA-N

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Packaging

Packaged under nitrogen, bottles are Sealed for Quality™

Legal Information

Genetron is a registered trademark of Honeywell International Inc.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Ozone 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

383.0 °F

flash_point_c

195 °C

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yun-Ru Chen et al.
Oncotarget, 7(2), 1984-1999 (2015-12-18)
Macroautophagy can promote cellular survival or death depending on the cellular context and its extent. We hypothesized that autophagy induction would synergize with a therapeutic agent targeting the autophagic cargo. To test this hypothesis, we treated breast cancer MDA-MB-231 cells
Wei Chen et al.
Autophagy, 10(7), 1272-1284 (2014-06-07)
Ribonucleotide reductase (RNR) plays a critical role in catalyzing the biosynthesis and maintaining the intracellular concentration of 4 deoxyribonucleoside triphosphates (dNTPs). Unbalanced or deficient dNTP pools cause serious genotoxic consequences. Autophagy is the process by which cytoplasmic constituents are degraded
H Vainio et al.
Toxicology, 18(1), 17-25 (1980-01-01)
Male Wistar rats were exposed to 200, 1000 or 2000 ppm of 1,1,2-trichloro-1,2,2-trifluoroethane vapor 5 days a week 6 h daily for 1 or 2 weeks. Proliferation and vacuolisation of the smooth endoplasmic reticulum (SER) of the liver was seen
T Kawakami et al.
Toxicology and industrial health, 6(3-4), 493-498 (1990-05-01)
The interaction of Freon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) and hypoxia on the heart conduction system was studied using electrocardiogram monitoring of isolated perfused rat hearts. Freon 113 (0.2 mM) alone elicited significant atrioventricular conduction delay (p less than 0.05) and heart rate
Chieh-Heng Wang et al.
Journal of chromatography. A, 1217(3), 353-358 (2009-12-08)
A gas chromatographic system was constructed to simultaneously measure ambient non-methane hydrocarbons (NMHCs) and halocarbons, which play significant roles in tropospheric ozone formation and stratospheric ozone loss, respectively. A heart-cut device based on a Deans switch was connected to two
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