Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

258555

Sigma-Aldrich

p-Phenylene diisothiocyanate

98%

Synonym(s):

1,4-Diisothiocyanatobenzene, Bitoscanate, PDITC

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C6H4(NCS)2
CAS Number:
4044-65-9
Molecular Weight:
192.26
Beilstein/REAXYS Number:
2414340
EC Number:
223-741-3
MDL number:
MFCD00004811
UNSPSC Code:
12352200
PubChem Substance ID:
24855647
NACRES:
NA.22

Quality Level

200

assay

98%

reaction suitability

reagent type: cross-linking reagent

mp

129-131 °C (lit.)

SMILES string

S=C=Nc1ccc(cc1)N=C=S

InChI

1S/C8H4N2S2/c11-5-9-7-1-2-8(4-3-7)10-6-12/h1-4H

InChI key

OMWQUXGVXQELIX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

p-Phenylene diisothiocyanate can be used in various applications including the following:
  • Synthesis of hydroxamate containing chelators for labeling antibodies with 89Zr and 68Ga for imaging with positron emission tomography (immunoPET).
  • Synthesis of fluorescent chemosensors for Hg2+ sensing in living cells.
  • Synthesis of polythiourea derivatives as capacitor dielectric materials.
  • Synthesis of 4-isothiocyanato-4′-nitrodiphenylamine, an anthelmintic agent, popularly known as amoscanate.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBL3523
STBK6184
STBJ7786
STBJ3479
STBH9984

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

New tris(hydroxypyridinone) bifunctional chelators containing isothiocyanate groups provide a versatile platform for rapid one-step labeling and PET imaging with 68Ga3+.
Ma MT, et al.
Bioconjugate Chemistry, 27(2), 309-318 (2015)
Rational design and synthesis of polythioureas as capacitor dielectrics.
Ma R, et al.
Journal of Material Chemistry A, 3(28), 14845-14852 (2015)
A New Synthesis Of 4-Isothiocyanato-4'-Nitrodiphenylamine (Amoscanate).
Viswanathan N and Desai RC.
Indian J. Chem. B, 20(4), 308-310 (1981)
Chengwei Li et al.
Nanoscale research letters, 15(1), 36-36 (2020-02-08)
Construct dielectric films with high energy density and efficiency are the key factor to fabricate high-performance dielectric film capacitors. In this paper, an all organic composite film was constructed based on high dielectric polymer and linear dielectric polymer. After the
Daniel Ramos-Sono et al.
PloS one, 15(10), e0241067-e0241067 (2020-10-29)
Tuberculosis (TB) is a major global public health problem with high mortality and morbidity. In low-middle income countries (LMIC) a large number of respiratory symptomatic cases that require TB screening per year demands more accurate, fast and affordable testing for
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service