258504

N⁴-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine

95%

• Synonym(s): Bz-DMT-dC
• Empirical Formula (Hill Notation): C₃₇H₃₅N₃O₇
• CAS Number: 67219-55-0
• Molecular Weight: 633.69
• Beilstein/REAXYS Number: 601627
• EC Number: 266-605-9
• MDL number: MFCD00010114
• UNSPSC Code: 12352100
• PubChem Substance ID: 24855646
• NACRES: NA.22

Properties

• assay: 95%
• form: solid
• functional group: amide; ether; hydroxyl; phenyl
• storage temp.: 2-8°C
• SMILES string: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2O)N3C=CC(NC(=O)c4ccccc4)=NC3=O)(c5ccccc5)c6ccc(OC)cc6
• InChI: 1S/C37H35N3O7/c1-44-29-17-13-27(14-18-29)37(26-11-7-4-8-12-26,28-15-19-30(45-2)20-16-28)46-24-32-31(41)23-34(47-32)40-22-21-33(39-36(40)43)38-35(42)25-9-5-3-6-10-25/h3-22,31-32,34,41H,23-24H2,1-2H3,(H,38,39,42,43)/t31-,32+,34+/m0/s1
• InChI key: MYSNCIZBPUPZMQ-VOTWKOMSSA-N

Description

General description

The 3′-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite derivatives of N⁴-benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine (DMT-dC^Bz) participates in Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides[1].

Application

N⁴-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine has been used as research tool for anti-viral and anti-cancer studies[2].

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H319,H410
• pcodes: P264 - P273 - P280 - P305 + P351 + P338 - P337 + P313 - P391
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges