250260
2-Naphthoyl chloride
98%
Synonym(s):
β-Naphthoyl chloride
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About This Item
Linear Formula:
C10H7COCl
CAS Number:
Molecular Weight:
190.63
Beilstein/REAXYS Number:
907776
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
98%
form
solid
bp
160-162 °C/11 mmHg (lit.)
mp
50-52 °C (lit.)
functional group
acyl chloride
SMILES string
ClC(=O)c1ccc2ccccc2c1
InChI
1S/C11H7ClO/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H
InChI key
XNLBCXGRQWUJLU-UHFFFAOYSA-N
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Application
2-Naphthoyl chloride has been used in:
- preparation of amide derivatives of the amphetamine enantiomers
- synthesis of 7-dimethylamino-2-methyl-3-naphthamido-phenothiazinium salt
- modification of self-assembled monolayer formed on silica surface from ((((aminoethyl)amino)-methyl)phenethyl)trimethoxysilane
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk_germany
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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I W Wainer et al.
Journal of pharmaceutical sciences, 73(8), 1162-1164 (1984-08-01)
A rapid and accurate method was developed for the determination of the enantiomeric composition of amphetamine preparations. Amide derivatives of the amphetamine enantiomers are first formed by using achiral 2-naphthoyl chloride. The resulting enantiomeric amides are then chromatographed on a
V L Lanchote et al.
Journal of chromatography. B, Biomedical applications, 685(2), 281-289 (1996-10-25)
Two methods were developed for the determination of mexiletine enantiomers in plasma samples suitable for studies on the stereoselective disposition of this drug. Both methods used fluorescence detection to improve sensitivity and selectivity. The direct enantioselective separation was based on
Tagbo Emmanuel Ezenwa et al.
Dalton transactions (Cambridge, England : 2003), 47(47), 16938-16943 (2018-11-18)
Selenium and sulfur derivatives of lead(ii) acylchalcogourato complexes have been used to deposit PbSxSe1-x thin films by AACVD. By variation of the mole ratio of sulfur and selenium precursors in the aerosol feed solution the full range of compositions of
A chemically modified graphite electrode for electrocatalytic oxidation of reduced nicotinamide adenine dinucleotide based on a phenothiazine derivative, 3-?-naphthoyl-toluidine blue O.
Persson B.
J. Electroanal. Chem. Interfac. Electrochem., 287(1), 61-80 (1990)
Formation and naphthoyl derivatization of aromatic aminosilane self-assembled monolayers: characterization by atomic force microscopy and ultraviolet spectroscopy.
Durfor CN, et al.
Langmuir, 10(1), 148-152 (1994)
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