242306

Allyl chloroformate

97%, for peptide synthesis

• Synonym(s): 2-Propen-1-yl chloroformate, Allyloxycarbonyl chloride
• Linear Formula: ClCOOCH₂CH=CH₂
• CAS Number: 2937-50-0
• Molecular Weight: 120.53
• Beilstein/REAXYS Number: 773915
• EC Number: 220-916-6
• MDL number: MFCD00000648
• UNSPSC Code: 12190000
• PubChem Substance ID: 24854549
• NACRES: NA.22

Properties

• product name: Allyl chloroformate, 97%
• vapor pressure: 3.67 psi ( 20 °C)
• assay: 97%
• form: liquid
• refractive index: n20/D 1.422 (lit.)
• bp: ~27 °C/11 mmHg (lit.)
• density: 1.134 g/mL at 20 °C (lit.)
• application(s): peptide synthesis
• storage temp.: −20°C
• SMILES string: ClC(=O)OCC=C
• InChI: 1S/C4H5ClO2/c1-2-3-7-4(5)6/h2H,1,3H2
• InChI key: CAEWJEXPFKNBQL-UHFFFAOYSA-N

Description

General description

Allyl chloroformate is an organic compound used to synthesize numerous compounds like allyl carbamates and allyl carbonates. Additionally, it can be used for the preparation of α-allyl carbonyls and α, β-unsaturated carbonyls.

Application

Allyl chloroformate is used in the synthesis of:

• Histones and their analogs.
• Alloc-TL monomer (N-(allyloxy)carbonylhomocysteine thiolactone) from cyclic thioester (d,l-homocysteine thiolactonehydrochloride).

Safety Information

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• hcodes: H226,H301,H314,H330
• pcodes: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 87.8 °F - closed cup
• flash_point_c: 31 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter